SCIENCE, MECHANISMS & SEQUENCING

7.50

Registration & Morning Coffee

8.50

Chairperson Opening Remarks

Shingo Arioka
Research Manager
Shionogi & Japan Microbiome Consortium

 

Host-Microbiome Interactions that Cause Disease

Session Purpose:

As the gut microbiome continues to be at the forefront of medical research, both the industrial and academic communities expect
that insights gained from microorganisms will soon become a critical component of health management across a gamut of critical
indications. However, the biggest hurdle in translating promising gut microbiome research into effective therapeutic candidates is
demonstrating the causative role of human microbiome in disease pathology. Although there are a growing number of microbiomebased candidates showing promising results in both pre-clinical and clinical settings, the approaches that are likely to have
well-validated mechanisms of action are limited. The purpose of this theme will be to review the current thinking in approaching the
human microbiome mechanistically and understanding both the academic and industrial perspectives on this important topic.

9.00

Microbiome, Host Genetics, and Metabolic Diseases

 

 

GwangPyo Ko
Founder and CEO
KoBioLabs

9.30

10.00

Impact of the Gut Microbiota in Korean Patients with GI Diseases

Changsoo Eun
Professor, Internal Medicine
Hanyang University College
of Medicine

10.30

Speed Networking Session

11.00

Morning Coffee & Refreshments Break

12.00

Faecalibacterium Prausnitzii Dynamics in the Human Gut Microbiome Underlying Atopic Dermatitis

Heenam Stanley Kim
Professor
Korea University, College of Health Sciences

Establishing Standardised Protocols for Microbiome Research

Session Purpose:

As the vast quantity of microbiome research continues to be translated into therapeutic, nutritional, biomarker and diagnostic
applications, the development of standard operating procedures continues to be crucial to ensure the reproducibility and
regulatory approval of these breakthrough products. The purpose of this theme will be to review the importance of creating
standard protocols to allow for greater comparability and reproducibility between studies without dampening cutting-edge
scientific innovation.

12.30

Introduction to the Japan Microbiome Consortium (JMBC): Establishing Standardized Protocols for Microbiome Research

Shingo Arioka
Research Manager
Shionogi & Japan Microbiome Consortium

13.00

Lunch & Networking

Sequencing, Bioinformatics & Big Data

Session Purpose:

The advent and accessibility of Next-Generation Sequencing (NGS) tools and bioinformatics analysis has provided the scientific
community a novel way to analyse communities of microorganisms and understand the functional relationship between microbial
dybiosis and disease pathogenesis, without the need of cultivation. More recently, researchers have moved beyond 16S sequencing
to integrate more complex analysis methods including shotgun metagenomics, metabolomics, metatranscriptomics etc. to move
towards species and strain-level profiling. The purpose of this theme will be to review the current NGS methodologies used to
analyse microbiome samples, how complex microbial datasets are being processed, and the technical challenges that need to be
overcome to assist future microbiome studies.

14.30

Integrated Omics Approach for Understanding the Gut Ecosystem and Mental Disorders

Hiroshi Ohno MD
Principal Investigator
RIKEN Center for Integrative
Medical Sciences

15.00

Metagenomic and Metabolomic Analyses Reveal Dynamic Shifts in Gut Microbiota along the Adenoma-Carcinoma Sequence in Colorectal Cancer

Takuji Yamada
Associate Professor
Tokyo Institute of Technology

15.30

Afternoon Coffee & Refreshments Break

16.00

Big Data and Multi-Omic Analysis of Microbiome Samples

Ken Kasahara
General Manager of Microbiome Area
Chitose Bio

16.30

Genomics and Bioinformatics in Microbiome Research

Jon Sik Chun
Professor
Seoul National University

17.00

Chairperson Closing Remarks

Shingo Arioka
Research Manager
Shionogi & Japan Microbiome Consortium

17.10

Close of Conference Day One & Reception Hosted By Microbiome Movement